ABSTRACT
Os autores mostram um caso de Hemossiderose Pulmonar Idiopatica na forma de inicio infantil, com uma sobrevida bem maior que a relatada na literatura. A crianca tem 5 anos de evolucao da doenca, e poucos sinais de cronicidade, apesar dos episodios graves de sangramento pulmonar, o que se opoe a descricao classica do quadro. Foi sugerida a alergia a proteina do leite de vaca como etiologia da doenca, e o tratamento foi feito com corticoide durante os surtos, com rapida resposta. Observou-se tambem varios episodios de recrudescen-cia por fuga da dieta, que nao ocorreram apos orientacao de uma equipe multidis-ciplinar. Os autores discutem ainda outros aspectos da doenca e fazem uma revi-sao da literatura.
Subject(s)
Child , Humans , Female , Hemosiderosis/etiology , Lung , Adrenal Cortex Hormones/drug therapy , Breast-Milk Substitutes/adverse effects , Hemosiderosis/therapyABSTRACT
Three trace elements, namely copper, zinc and iron were determined in nephrotic children under corticosteroid therapy for variable periods. Serum copper, zinc and iron were significantly decreased in nephrotic children before starting and medication [Group II]. Nephrotic cases with proteinuria receiving corticosteroids for 2 weeks [Group III] showed a significant decrease in serum copper and ceruloplasmin while iron and zinc were not significantly changed. Cases of nephrotic syndrome under corticosteroid therapy for one month with absent proteinuria [Group IV] showed a significant decrease in both copper and iron. Serum zinc increased significantly in nephrotic cases under corticosteroid therapy for two months [without proteinuria] [Group V.]. While copper and ceruloplasmin were still significantly decreased without significant changes in serum iron level. These results were discussed